Ohio State vs. Penn State Prediction, Odds, Picks - November 1, 2025

Preview the Nov. 1 matchup between the Ohio State Buckeyes and Penn State Nittany Lions with predictions, odds, over/under, spread, betting lines and more.

Social Media Reactions to Penn State vs. Ohio State

Championship-level response by Ohio State. The Penn State defense just doesn’t have it so far today. Brutal pass interference penalty on AJ Harris on 3rd down. Ohio State has it 1st and goal at the 8. Meanwhile Ohio State can get 50 yards on us whenever they want with the deep ball. Infuriating. https://t.co/eyYfBvHbpw

What Ohio State Buckeyes players had to say after Penn State victory

Up 17-7 and in a two-minute drill with a potent passing attack, the energy at Ohio Stadium was pulsing, knowing that one more score could put the game away. Sur

Penn State football team’s report card vs. Ohio State

COLUMBUS, Ohio – Grading the Penn State football team on its 38-14 loss to Ohio State Saturday at Ohio Stadium: C: Ethan Grunkemeyer again showed pocket presence in a difficult environment, made some nice throws and missed a few. C: Kaytron Allen and Nick Singleton accounted for 132 of Penn State’s 200 total yards and both of its touchdowns.

Ohio State’s romp over Jim Knowles, Penn State shows stability goes beyond who calls plays

Ohio State is a self-sustaining program that doesn't live or die by one coordinator. That's harder than it looks.

How Penn State's Ethan Grunkemeyer Navigated a Tough Day at Ohio State

While Penn State’s defense was on the field, Grunkemeyer sat at the edge of one of the benches, quarterbacks coach Danny O’Brien on his right. He often spoke with receivers sitting on the bench to his left while Ohio State marched down the field, connecting with receivers easily.
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Ohio State QB Julian Saying surges as new Heisman favorite

Ohio State QB Julian Saying surges as new Heisman favorite originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. Ohio State quarterback Julian Sayin has surged to the top of the Heisman Trophy odds following another dominant performance in the Buckeyes’ 38-14 win over Penn State on Saturday.

As expected, Penn State opens as a significant underdog vs. unbeaten Indiana on Saturday

Indiana (9-0, 6-0), a 55-10 winner over Maryland on the road on Saturday, own impressive victories over Illinois (63-10), Iowa (20-15) and Oregon (30-20). The Hoosiers, coached by Curt Cignetti, piled up 588 yards of total offense vs. the Terrapins in College Park, Md.

Ohio State vs. Penn State prediction: Who wins, and why?

Talk about teams going in different directions. Ohio State is the reigning national champion and the favorite to do it again, while Penn State was a preseason t
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