Cells in the human body accumulate cancer-promoting mutations throughout their lifespan, yet these mutations rarely drive tumour formation. Tumours in a given tissue usually originate from a specific ...

The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...

In yeast, the CDK and cyclin proteins that drive cell division activate first in the nucleus — a different location in the cell from where was previously thought. James E. Ferrell Jr is in the ...

The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...

Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria. The ...

Inside the human airway, a certain cell type reigns supreme: multiciliated cells, decorated with dozens of hair-like cilia all beating in tandem. These cells are responsible for clearing out foreign ...