When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Two mysterious human relatives left their genetic footprints in the modern human genome alongside the DNA of Neanderthals and Denisovans, underscoring the fact that our ancestors interbred with many ...

At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, particularly in tissues such as the bone marrow, intestine and skin; neurons and heart ...

In the 1930s, Hermann Muller was the first researcher to note that the ends of chromosomes had unique properties. Muller ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Researchers built an in-cell ELISA that measures the DNA damage marker γH2AX in stable, non-proliferating human hepatocytes ...