Context: Fatal familial insomnia (FFI) is a genetically transmitted neurodegenerative prion disease that incurs great suffering and has neither a treatment nor cure. The clinical literature is devoid ...

The first sign of my father’s decline came at his lunchtime basketball game. At 66-years-old, he’d always been healthy and active. Then he tripped during a game. A few weeks later, he forgot where to ...

Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of muscle groups and/or entire limbs. The three major phenotypes of genetic ...

"I just don't understand it. According to the history given by her friend, she hasn't slept in eight days and there have been no behavioral indications that she has slept since being admitted. We'll ...