The results of the Valsartan/HCTZ Combination Therapy in Patients With Moderate to Severe Systolic Hypertension (VALOR) study [1] show that valsartan 160 mg once daily is safe and effective in older ...

The trials were multicentre, double-blind, double-dummy, randomized, parallel group studies that compared the efficacy and safety of telmisartan with HCTZ 80/25 versus valsartan–HCTZ 160/25 as well as ...

The ESH-ESC guidelines do not provide recommendations on the individual members of drug classes, but recently a meta-analysis of ambulatory BP studies involving ARBs has shown that the drug used and ...

The primary end point was the proportion of patients achieving goal mean trough SiDBP (<90 mm Hg) after 4 weeks of therapy with either losartan 50 mg/HCTZ 12.5 mg or a losartan monotherapy regimen ...

Combination therapy using irbesartan and hydrochlorothiazide was shown to effectively lower blood pressure levels in a large group of hypertensive patients. “The INCLUSIVE [Irbesartan/HCTZ blood ...

Aliskiren 150 mg, hydrochlorothiazide (HCTZ) 12.5 mg; tabs. Tekturna HCT combines the antihypertensive drugs aliskiren, a direct renin inhibitor, and the thiazide diuretic, hydrochlorothiazide (HCTZ).

CHICAGO, IL—Chlorthalidone does not reduce major adverse cardiovascular events compared hydrochlorothiazide in older, predominantly male military veterans with hypertension, according to the ...

HYDROCHLOROTHIAZIDE (6-chloro-7-sulfamyl-3,4,dihydro-l,2,4, benzothiadiazine-1,1,-dioxide) is the 3,4,dihydro derivative of chlorothiazide wherein the 3,4 double bond is saturated by two hydrogen ...

The first fixed-dose combination involving Novartis’first-in-class oral renin inhibitor, Tekturna with hydrochlorothiazide (HCT)was approved in the USin January 2008. A single-tablet combination with ...