DNA ligases are ubiquitous enzymes that catalyse the formation of phosphodiester bonds between adjacent 5′‐phosphate and 3′‐hydroxyl termini in double-stranded DNA. The canonical ligation cycle ...
While the central dogma of molecular biology outlines the linear flow of genetic information from DNA to RNA to proteins (black lines), glycomics introduces a “3rd code of life”—glycans—that operates ...
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