Modic changes refer to the presence of subchondral changes of the vertebral endplate detected on magnetic resonance imaging. Previous studies have linked Modic changes to an increased risk of severe ...

In this 2-year follow-up study, we found a significant positive association between the change in the extent of M1 and change in ODI. We also found a positive association between the change in the ...

Background The association of Modic changes (MC) with low back pain (LBP) is unclear. The purpose of our study was to investigate the associations between the extent of Type 1 (M1) and Type 2 (M2) MC ...

August 20, 2024 — Among patients undergoing lumbar spinal fusion, the presence of Modic changes is associated with differences in microbial diversity and metabolites in the lumbar cartilaginous ...