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Week 10 NFL odds, lines, best bets, predictions: Computer model likes Buccaneers and 49ers
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

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2025 NFL Odds Week 10: Lines, Spreads for all 14 Games
Lions vs. Commanders prediction, pick, odds for Sunday's NFL Week 10 game
Broncos' Defense Shines in 10-7 Squeaker Over Raiders Despite Offensive and Special Teams Struggles
Denver's defense bailed out the Broncos in a 10-7 squeaker over the reeling Las Vegas Raiders on Thursday night, sacking Geno Smith six times to atone for spotty performances on offense and special t...

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NFL Playoff Picture 2025-26, Standings, Bracket Scenarios After Raiders vs. Broncos
Patriots vs Buccaneers Props & Best Bets for Week 10
Broncos vs. Raiders Highlights, Top Plays: Denver Wins an Ugly One
Denver blocked a punt to set up the deciding field goal.

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Recap of Broncos' ugly win over Raiders on 'Thursday Night Football'
Broncos edge Raiders for seventh straight win: Live updates and reaction from NFL ‘Thursday Night Football’

NFL Week 10 betting, odds, lines: 5 biggest storylines, including some confusing odds on the Chiefs

Here are the five betting storylines going into NFL Week 10, with all odds from BetMGM: It's jarring to see anyone but the Chiefs favored to win the AFC West. They've won it nine seasons in a row, and were favored to win a 10th.
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Opening NFL Week 10 Odds and Betting Lines: Maye & Pats Slight Dogs in Tampa

Get the opening NFL Week 10 odds with point spreads, Over/Unders, and football moneylines for every matchup starting on Nov. 6, 2025.

Week 10 NFL betting guide, props, spreads: Model, expert, parlay, DFS and season-long fantasy picks revealed

Other NFL lines of a field goal or less include Texans vs. Jaguars (-1.5), with C.J. Stroud (concussion out SportsLine's model has returned well over $7,000 on top-rated NFL betting picks since its inception,
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