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Predictions, picks and odds for NFL Week 10 game

2025 NFL Week 10 Expert Picks

After an 11-2 run for NFL favorites against the spread in Week 8, underdogs barked back in the previous slate, going 9-6, and three of them covered lines that were 8.5 points or more.

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Self-learning AI releases NFL picks, score predictions every Week 10 game

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Eagles at Packers: Predictions, picks and odds for Monday Night Football Week 10

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NFL Week 10 upset predictions: Indianapolis Colts vs Atlanta Falcons start time, odds, where to watch, stream

The Indianapolis Colts (7-2) play the Atlanta Falcons (3-5) in Berlin, Germany, in NFL Week 10 action.

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2025 NFL Week 10 Winners and Losers and Top Takeaways

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NFL 2025 Week 10 odds: Lions vs. Commanders spread, line, over/under

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NFL 2025 Week 10 odds: Chargers vs. Steelers spread, line, over/under

Los Angeles has an against-the-spread record of 4-5-0 so far this season.

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Broncos edge Raiders for seventh straight win: Live updates and reaction from NFL ‘Thursday Night Football’

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NFL 2025 Week 10 odds: Seahawks vs. Cardinals spread, line, over/under

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Full list of Week 10 straight-up picks with confidence levels

We make picks for all 14 NFL games with levels of confidence ahead of Week 10. The NFL heads into Week 10 with the playoff race heating up. Nobody will be clinching playoff berths this week, but we’re coming off a week in which some teams firmed up their positioning while others hurt their chances.

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NFL Week 10 picks, odds, best bets: J.J. McCarthy surprises Lamar Jackson, Steelers and Eagles score upsets

I'll bite on the Panthers following their upset win over the Green Bay Packers. This is actually the first time Carolina has been favored over New Orleans since 2017! It's warranted, as the Saints are 2-7 ATS on the year, which is the worst mark in the NFL .