Nuclear pore complexes (NPCs) control biomolecular transport in and out of the nucleus. Disordered nucleoporins in the complex’s pore form a permeation barrier, preventing unassisted transport of ...
Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules
COVID-19 has seriously threatened public health, and transdermal vaccination is an effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum corneum to allow passive ...
Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...
Bacteria and yeast need to prevent leakage of numerous small molecules through their cell membrane. Biochemists have studied how the composition of the membrane affects passive diffusion and the ...
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