Mediator is a multiprotein complex that transmits gene regulatory signals from transcription factors to RNA polymerase (Pol) II 1,2,3,4. Yeast Mediator comprises 25 subunits, of which 11 are essential ...
The general transcription factor TFIID provides a regulatory platform for transcription initiation. Here we present the crystal structure (1.97 Å) and NMR analysis of yeast TAF1 N-terminal domains ...
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