Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to ...

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed. Although biophysicist Bernard Katz from ...