San Francisco 49ers wide receiver Ricky Pearsall missed his second straight practice this week, with just one remaining, as the team prepares for its Monday night matchup against the Indianapolis Colts.

The San Francisco 49ers will hold three full practices this week as they prepare for their Week 16 matchup against the Indianapolis Colts. Head coach Kyle Shanahan, defensive coordinator Robert Saleh, offensive coordinator Klay Kubiak, and quarterback Brock Purdy are scheduled...

Although 49ers receiver Ricky Pearsall reinjured the knee that kept him out of six games earlier this season, coach Kyle Shanahan hasn't ruled out his return against the Colts on Monday.

The Kansas City Chiefs can't catch a break in the final three weeks of the 2025 NFL season. After being eliminated from playoff contention against the Los Angeles Chargers on Sunday, losing quarterback Patrick Mahomes with a season-ending ACL injury and seeing Xavier Worthy leave the game with a concussion,

GM John Lynch defends WR Ricky Pearsall, pushing back on the injury-prone label as San Francisco prepares for a pivotal game vs. Colts.

The San Francisco 49ers enter Week 16 at 10–4, firmly in playoff position with three games remaining. Read on for 49ers key players to watch as San Francisco faces the struggling Indianapolis Colts.

Chris Simms and Mike Florio preview Chiefs vs. Titans in Week 16, which will be Kansas City's first game without Patrick Mahomes.