The Week 10 NFL schedule kicks with the Denver Broncos vs. the Las Vegas Raiders in an AFC West showdown on 'Thursday Night Football.' The games starts at 8:15 p.m. ET, and daily Fantasy football players will have to be creative when looking for production since this game only has an over/under of 42.

The Underdog promo code NEWSWEEK will give new users a $100 bonus for use across NBA, NHL and NFL Week 10 picks this weekend.

With the NFL season underway, pinpointing the best bets every week can be challenging. Let's have a look at which upcoming potential upsets to target.

All Week 10 picks appear below. We disagree on four of the games. Raiders at Broncos (-9.5) The only thing compelling about this one will be whether Tom Brady is in the coaches’ booth with his cloned canine.

If the regular season were to end today (and we know, it doesn't), the New York Giants would select fifth overall in the 2026 NFL draft,