Having considered localization of respiratory functions in mitochondria and in prokaryotic cells, it's time to return to the eukaryotic context and follow a molecule of pyruvate across the inner ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. The manuscript by Brothwell and colleagues describes a central ...

This study presents a valuable finding on the importance of the plasma metabolome in glaucoma risk prediction. The evidence supporting the claims of the authors is solid and the work offers insights ...

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Scientists have cracked the structure of the mitochondrial pyruvate carrier, a fuel gate inside our cells, after 50 years of speculation. The discovery could revolutionize treatment strategies for ...

Pelage Pharmaceuticals presented positive translational and Phase 1 clinical data demonstrating the company’s novel small molecule therapy PP405 reactivates dormant hair follicle stem cells to trigger ...

Neuronal maturation is the phase during which neurons acquire their final characteristics in terms of morphology, electrical activity, and metabolism. However, little is known about the metabolic ...

ABSTRACT: Over the last 20 years, it has emerged that, while surgical revascularisation of extensive ischaemic heart disease may have prognostic advantages, the main issues considered regarding ...