NFL Week 10 picks: Rams get revenge on 49ers
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An all-encompassing look at the matchups to exploit or avoid and lineup locks in fantasy, as well as projected scores for all NFL games.
However, Cleveland Browns rookie Dylan Sampson is a viable boom-or-bust play in PPR leagues only. While Sampson is firmly behind starter Quinshon Judkins on the depth chart and often plays behind Jerome Ford as well, Cleveland may look to get him more reps coming out of the bye.
There's one NFL game in particular that stands out in Week 10, with FOX Sports' Tom Brady calling it the "game of the year."
All odds referenced are courtesy of BetMGM as of publish time.
It's Week 10 of the 2025 fantasy football season, and the stretch run for the fantasy playoffs is almost here. For many managers, the pressure to get a win this week is immense.
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How to watch NFL football: Week 10
Some of the league’s biggest stars have the chance to hit career milestones in their games this weekend as the NFL season rolls on.
Week 10 of the NFL season is here, and it's already shaping up to be another prime week for fantasy managers. From breakout stars to disappointing dud performances, making the right start or sit calls can make or break your lineup,
Kickoff from U.S. Bank Stadium in Minneapolis is set for 1 p.m. ET. The Ravens are 4.5-point favorites in the latest Ravens vs. Vikings consensus odds at SportsLine and the total comes in at 49.5. Baltimore is a -222 money line favorite while Minnesota is the +181 home underdog.
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