The β-lactam ring is part of the core structure of several antibiotic families, the principal ones being the penicillins, cephalosporins, carbapenems, and monobactams, which are, therefore, …

All members of the superfamily of antibiotics known as “beta-lactams” have a core structure consisting of a 4-member “beta-lactam” ring (Figure 1). Figure 1. Core structure of beta-lactam …

Figure: β-Lactam: β-Lactam ring is a four-membered lactam. The β-lactam ring is part of the core structure of several antibiotic families, the principal ones being the penicillins, cephalosporins, …

Up to 1970, most β-lactam research was concerned with the penicillin and cephalosporin groups, but since then, a wide variety of structures have been described. This service is an Elixir Core …

May 15, 2025 · The β-lactam ring serves as the central structure in important antibiotics such as penicillins and cephalosporins, while certain monocyclic β-lactams have demonstrated the …

Jul 24, 2025 · The beta-lactam ring is a distinct four-membered cyclic amide structure, often visualized as a square-shaped molecular component. This chemical arrangement serves as …

Jun 20, 2012 · Of the β-lactam antibiotics that are currently available, all feature the reactive β-lactam ring system, a highly strained and reactive cyclic amide. There are five relevant ring …

Jan 15, 2025 · This review explores the mechanisms, clinical applications, resistance patterns, and collaborative healthcare strategies for beta-lactam antibiotics, emphasizing their pivotal …

Mar 1, 2023 · This review emphasizes the three-dimensional structural characteristics of β-lactam antibiotics regarding the overall scaffold, working mechanism, chemical diversity, and …

By definition, all β-lactam antibiotics have a β-lactam ring in their structure. The effectiveness of these antibiotics relies on their ability to reach the PBP intact and their ability to bind to the PBP.