Somatostatin is then carried to the anterior pituitary gland, where it inhibits the secretion of growth hormone from somatotrope cells.

Apr 25, 2022 · In your hypothalamus, somatostatin stops the release of hormones your pituitary gland makes, including growth hormone, thyroid-stimulating hormone and prolactin.

Somatostatin from the hypothalamus inhibits the pituitary gland’s secretion of growth hormone and thyroid stimulating hormone. In addition, somatostatin is produced in the pancreas and inhibits the …

Third, growth hormone and somatomedins together signal to the hypothalamus to produce somatostatin, which is also called the growth hormone inhibiting hormone. Somatostatin acts like a lawyer that tells …

In mammals, somatostatin originates from pre-prosomatostatin and is processed to a shorter form, i.e., somatostatin-14, and a longer form, i.e., somatostatin-28. The two peptides repress growth hormone …

Dec 19, 2025 · The name somatostatin, essentially meaning stagnation of a body, was coined when investigators found that an extract of hypothalamic tissues inhibited the release of growth hormone …

Somatostatin (SS) is a peptide produced by several tissues in the body, including the hypothalamus. Somatostatin inhibits growth hormone release in response to GHRH and to other stimulatory factors …

Aug 5, 2025 · Somatostatin exerts its inhibitory effects across multiple bodily systems. In the brain, hypothalamic somatostatin specifically inhibits the release of growth hormone (GH) and thyroid …

In neuroendocrine regulation, somatostatin inhibits the secretion of growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, insulin, and glucagon through activation of the five G-protein …

Nov 18, 2025 · Somatostatin holds an interesting place in gastrointestinal endocrinology. Originally discovered as an inhibitor of growth hormone release [1], it is now known to inhibit a variety of …